CMV IgM and IgG (Cytomegalovirus)

Definition

CMV tests detect antibodies and viral markers in the blood (and also in sputum, cerebrospinal fluid or other body fluids):

AntibodyGeneral meaning
IgMSuggests a new or current infection
IgGSuggests past exposure or chronic infection

Purpose

For immunocompromised people (HIV, cancer patients), organ transplant recipients, pregnant women with symptoms of CMV infection, and newborns with signs of infection.

Special importance in pregnancy: a pregnant woman can pass the virus to the fetus; in severe cases this can lead to miscarriage or stillbirth.

Results

The test result can show whether a person has had a CMV infection before.

Risks and Limitations

Critical limitation, stated clearly in the source:

The tests cannot show whether the infection is current, past or reactivated.

In other words, a positive CMV result does not tell you when the infection occurred. If symptoms or risk factors are present, additional testing is needed for a definitive diagnosis.

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