Total Protein and A/G Ratio

Definition

Measures the total protein in the blood and compares its two main types: albumin makes up most of the protein in the blood, and the remainder is called globulin. The A/G ratio is the ratio of albumin to globulin.

Purpose

Screening for nutritional deficiency, liver dysfunction and kidney disease. As part of routine check-ups, or for symptoms such as swelling, fatigue, unexplained weight loss, jaundice or blood in the urine.

Results

FindingWhat it suggests
Low total proteinLiver disease, kidney disease, malnutrition, malabsorption
High total proteinInfections (HIV, hepatitis) or multiple myeloma
Low A/G ratioAutoimmune diseases, liver disease, kidney disease
High A/G ratioGenetic disorders or leukemia

Normal Values

Laboratory specific.

Risks and Limitations

Abnormal results may be a sign of a serious health problem, but for correct interpretation, symptoms, medical history and other tests must be evaluated together.

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