Calcium

Definition

Measures calcium in the blood in two forms:

MeasurementWhat it covers
Total calciumAll of the bound (attached to proteins) + free/ionized (unbound) calcium
Ionized calciumOnly the unbound calcium. Ordered when total calcium is abnormal or in special situations

Normally your body tightly controls the balance between bound and ionized calcium, so a total calcium test gives a good estimate of how much ionized calcium you have.

Purpose

Routine metabolic panel screening; diagnosis of conditions affecting the bones, kidneys, thyroid and parathyroid glands; evaluation of symptoms of abnormal calcium; monitoring of known diseases (kidney/thyroid disease, malnutrition, cancer).

Results

  • High (hypercalcemia), hyperparathyroidism, certain cancers, Paget's disease or excess vitamin D
  • Low (hypocalcemia), low blood protein, hypoparathyroidism, inadequate calcium intake, vitamin D or magnesium deficiency, pancreatitis, kidney disease

Normal Values

Laboratory specific.

Risks and Limitations

A frequently confused point:

This test does not tell you how much calcium is in your bones.

Bone health requires a bone density measurement (DEXA). Someone with normal blood calcium can have osteoporosis.

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