Hereditary thrombophilias are conditions in which the blood's tendency to clot is increased, potentially leading to serious consequences such as blocked blood vessels, organ clots, pregnancy loss and intrauterine growth restriction. The following gene regions are examined to assess these risks:
- Factor V Leiden (G1691A)
- Factor II – Prothrombin (G20210A)
- MTHFR C677T and MTHFR A1298C
By carefully assessing the genetic risks of clotting disorders, clinicians can offer patients personalized treatment plans. Adding anticoagulant therapy, especially during pregnancy, helps manage these risks effectively.